Farming

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In Divinity Original Sin 2, most of the Loots and quest rewards are random. However, if you have high Lucky Charm ability, the chances of finding high-tier equipment will be greatly improved.(The highest points you can invest on this ability is 5, however some equipment can further improve it.With 6 or Higher Lucky Charm, you can get highest rank items from looting.)

 

Farming Guides

 

Equipments can be found at any lootable place, even a armor can be hidden in a pile of books. If you have high Lucky Charm Abilities, dont waste it. (There is a mirror on Lady Vengeance that allows you to change your character's abilities and attributes. You can make your character with high Lucky Charm and high Wits just for better loots. Then change them back.)

(Note: though rare, but some items are buried and require high wits to find.)

Alternatively, you can recruit adventurers on Lady Vengeance to help you loot the treasures.

Useful tips

• You should always buy/sell with your character who has Bartering(Civil Action) and sell your items to NPCs with which you have a good reputation.
• Pick up or buy cheap materials like Nails, Broken Bottles and combine them with empty grenades to make Nailbomb Grenades and Armor-Piercing Grenades which sell for at the least 5 times the price of the materials.
• Same thing with Intestines and Rotten Eggs combine them with Empty Canisters for Chemical Warfare Grenades which sell for a good price.
• Almost every herb can be combined with empty potion bottles to make potions which can be sold for more profit, you can also upgrade your minor healing potions to Healing Elixir by combining them with Yarrow Flowers which are worth even more.
• Arrowhead(1g) combined with Fire Resistance Potion(8g) give Explosive Arrowhead which you can combine with Arrow Shaft(1g) for Explosive Arrow(61g) which are worth 6 times the materials used. You can make your own Fire Resistance Potions by combining Guepinia Mushroom(1g) and Empty Potion Bottle(1g).
• Logs can be combined with a dagger to make 2 Wooden Branches + 1 Wood Chips, you do not lose the dagger.
• Sharp Stones can be combined with a Wooden Branch for a Sharp Stone on a Stick which sells for more.
• Cloth and Leather Scraps combined with a Tong for a Big Tongs Roped Together which sells for more.
• Soap + any key gives a Lockpick, you do not lose the key or Nails + Repair Hammer gives 4 lockpicks, you do not lose the Hammer. Lockpicks sell for more than Soap or Nails and this means you should never have to buy any lockpick.
• Mortar and Pestle + Bone/Skull gives Bonedust and Mortar and Pestle + Stardust Herb gives Stardust. Bonedust + Stardust gives Pixie Dust which sells for more.
• But get a coin purse, fill with much gold as you have. Sell it, then steal it back. Basically you will only steal the purse value(like 20g) and not the inside value. So you can steal all your money back. 

 

Anathema

Only a few items in Divinity Origianl Sin 2 have static locations, one of them being the Anathema, arguably the best two-handed weapon in the game. (Anathema can turn the final battle into an easy one, but your character needs to master Two-handed ability in order to maximize its power)To acquire this weapon, you need to complete the quest All In The Family.

The first time you board the Lady Vengeance, you will meet a necromancer named Tarquin, do not kill him for he is key in many quests. (and some others)

When you arrived at Reaper's Coast, you will meet Tarquin again at the gate of Stonegarden. This time he will give you the quest All In The Family, you need to investigate a family crypt and retrieve something for him.

The key to the family crypt comes from a petrified sourceress, Qauna, found in the crypt guarded by the hound (the crypt is close to and directly north of the family crypt and is flanked by two knight statues). Cast Bless on her inside the crypt to depetrify her and she will talk to you. If you fight with her she will spawn undead minions, but kill her and they will disappear so just focus her down.

(You can lockpick the door if you failed to find the key)

Next, head to the family crypt and open the door. In the first room of the family crypt, there are two buttons on the wall, you need to get close to find them. Press these the buttons to open the stone gate.

Teleport one of your companions into the third room and have them step on the pressure plate. Then cast Spirit Vision (Learned in Powerful Awakening), you will see three levers on the wall in the second room with the sarcophagus.  Press the levers (middle-left-right) to reveal a secret hatch. If you have already touched the levers since stepping on the plate, in some other order, then you need to "reset" the middle lever. Pull the middle lever until water comes out, then do left, then do right.

There's a treasury under that hatch, use your character with highest lucky charm to loot them. The artifact is in the coffin. If your character is a lizard, he/she will recognize the language it says.

When you try to leave the tomb, all of the clay sentinels will revive and attack you.

Report to Tarquin, he will tell you the other piece of the artifact is on Bloodmoon Island.

When you travel to Bloodmoon Island, you can find a hatch on its northeast corner, you need high enough wit to spot it buried:

Inside the vault is the other half of the artifact.

When you have both halves of the artifact, talk to Tarquin. (Sometimes he is not at the gate of stonegarden, you can find him on Lady Vengeance, near the boat. If you travel to Lady Vengeance by waypoint, he's right next to you.)

If you give Tarquin the pieces, he will repair it at ACT IV (The Arx).

 

Swornbreaker

Swornbreakers are unique weapons in Divinity Original Sin 2, combat-wise, they are not very powerful. But they are related to many quests, use them wisely can bring you lots of rewards, and can even alter the ending.

There are two Swornbreakers in D:OS 2. One can be forged on Nameless Isle, one can be found in The Vault of Linder Kemm.

To forge the Swornbreaker, you need three pieces, the tablet found in Ancient Temple (or reciepe given by Ryker, or Almira), the shaft in Sallow Man's war room, and the blade in the Academy Arena.

To find the tablet, you need to explore the Blackpits Mine at the Reaper's Coast.

At the end of the Blackpits Mine, there is the gate to Ancient Temple. Use Pyro skills to destory the gate.

In the heart of Ancient Temple, there is a puzzle, and seven shrines of seven gods, you need to activate them in the correct order. 

The riddles are:

"Our first lord babes with power glowed, our second's born in blood that flowed. Our third's young to the wind returned, our fourth's to glowing flames adjourn. Our fifth lord's cubs with minds were blessed, our sixth's had brawn beyond the rest. Our seventh's brood spread from earth to glen, and thus no king shall rise again."

The key to the puzzle is within a book on a corpse within the Ancient Temple chamber. It will say on the second page that each god is a representation of an element or power:

Rhalic-Earth
Duna-Air
Tir Cendelius-Blood
Zorl Stissa-Fire
Vrogir-muscle
Xantessa-Mind
Amadia-Magic

The correct order is: Amadia, Tir, Duna, Zorl, Xantessa, Vrogir, and finally Rhalic.

After you hit all the pillars in the correct order, an Eternal will appear, and have an interesting conversation with your god. You need to defeat the Eternal and her stalkers. Loot the place and you will find the tablet. (You can keep the tablet, or give it to Ryker or Almira for recipe, either way you can create the Swornbreaker.)

The Nameless Isle has two necessary pieces of Swornbreaker, the first one can be found at Sallow Man's war room.

East of the Temple of Rhalic, there is a troll guarding a cave:

Simply kill him, or pass a speech check to convince him to let you in the cave (you will gain 20,075XP for killing him). If you kill him, you will need to nuke him down as he regenerates around 3000 health per turn. Enter the cave and either use the Cowl of the True Sight right after the altar, towards the fake wall, or interact with the altar and drop the head into it (this will not destroy the head, don't worry). The path to the Sallow Man will be clear.

The swornbreaker piece is inside a chest in the war room. Either you sneak there, or kill the Black Rings to get it.

Another piece of Swornbreaker, can be found in the Academy Arena (guarded by some Automatons):

Once you have all three pieces, you can combine them to create Swornbreaker.

In ACT IV (The Arx), there is another Swornbreaker:

(The Swornbreaker is held by the statue)

Swornbreakers can free yourself from the God King (if you swear loyalty to God King in The Covenant), Windego (Mercy is Power), or Red Prince's Lover (The Consulate).

Other Treasure Spots

In Divinity: Original Sin 2, there are lots of locations contain valuable items/equipments. Consider explore these places for addtional lootings.

There are two caves on Nameless Isle not related to quests, but worth exploring

 

(This cave is on the south of the island, near the shadow prince.)

The second cave:

(This cave on the north of the island, you can teleport there from the platforms of the elven temple. Inside the cave, there are multiple constructs guarding a nice sword. Make sure your character has enough strength to lift it.)