Mystical Giant Venom Rune is in the Runes category in Divinity: Original Sin 2. Runes can grant bonues when slot in weapons, armor or jewelry.
Where to find:
- Sold by Merchants
- Can be crafted: Giant Venom Rune + Mystical Rune Frame
- Found randomly around the game world
- Sometimes available as a quest reward
Note and Trivia about Mystical Giant Venom Rune
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