Runes in Divinity: Original Sin 2 can be found on this page.
Runes
You can enchant Weapons and Armor with Runes to imbue or amplify their current state for resistances, attribute points, combat points, stat buffs, or varying damage types.
Tips
These are preliminary tips before you attempt to begin accumulating runes and craft higher tiers.
- Runes may be freely slotted and removed as they are not destroyed upon extraction.
- Why does this matter? It's efficient to accumulate a small quantity of higher tier runes.
- Runes and Frames will appear periodically in a Trader's inventory.
- Typically this is the same person.
- Frames may not be reused.
- Why does this matter? Placing frames on low tier runes may affect availability of frames when higher tier runes become available.
- Masterwork Runes in Items increase the Physical/Magic Armor of that item.
- This means using a Masterwork Runes on a Armor pieces with low physical armor is a waste of a runeslot (unless you just want 3 Strength).
Relevant Items
Rune Variations
Final Product |
Ingredient 1 |
Ingredient 2 |
Ingredient 3 |
Weapon Slot Effects |
Armor Slot Effects |
Amulet/Ring Slot Effects |
 Source Orb |
-- Cannot -- | -- be -- | -- crafted -- | Venomous Aura | Mass Cleanse Wounds | Evasive Aura |
 Small Flame Rune |
 Any Wood |
 Any Oil Source |
 Pixie Dust |
+9% damage as Fire damage | Fire Resistance: +5% | Critical Chance: +3% |
 Small Frost Rune |
 Any Water Source |
 Any Metal Item |
Pixie Dust |
+9% damage as Water damage | Water Resistance: +5% | Movement: +0.25 |
 Small Masterwork Rune |
 Livewood Log |
 Any Wine Source |
Pixie Dust |
+9% damage as Physical damage | Maximum Physical Armour: +9% | Maximum Magic Armour: +9% |
 Small Rock Rune |
 Any Rock |
 Any Beer Source |
Pixie Dust |
+9% damage as Earth damage | Earth Resistance: +5% | Maximum Vitality: +9 |
 Small Thunder Rune |
Any Water Source |
 Any Gold Item |
Pixie Dust |
+9% damage as Air damage | Air Resistance +5% | Dodging: +3% |
 Small Venom Rune |
  Any Bone |
 Any Poison Source |
Pixie Dust |
+9% damage as Poison damage | Poison Resistance: +5% | Accuracy: +5% |
| - | - | - | - | - | - | - |
 Medium Flame Rune |
Small Flame Rune |
Small Flame Rune |
Pixie Dust |
+11% damage as Fire damage | Fire Resistance: +7% | Critical Chance: +4% |
 Medium Frost Rune |
Small Frost Rune |
Small Frost Rune |
Pixie Dust |
+11% damage as Water damage | Water Resistance: +7% | Movement: +0.5 |
 Medium Masterwork Rune |
Small Masterwork Rune |
Small Masterwork Rune |
Pixie Dust |
+11% damage as Physical damage | Maximum Physical Armour: +13% | Maximum Magic Armour: +13% |
 Medium Rock Rune |
Small Rock Rune |
Small Rock Rune |
Pixie Dust |
+11% damage as Earth damage | Earth Resistance: +7% | Maximum Vitality: +23 |
 Medium Thunder Rune |
Small Thunder Rune |
Small Thunder Rune |
Pixie Dust |
+11% damage as Air damage | Air Resistance: +7% | Dodging: +4% |
 Medium Venom Rune |
Small Venom Rune |
Small Venom Rune |
Pixie Dust |
+11% damage as Poison damage | Poison Resistance: +7% | Accuracy: +8% |
| - | - | - | - | - | - | - |
 Large Flame Rune |
Medium Flame Rune |
Medium Flame Rune |
Pixie Dust |
+13% damage as Fire damage | Fire Resistance: +9% | Critical Chance: +5% |
 Large Frost Rune |
Medium Frost Rune |
Medium Frost Rune |
Pixie Dust |
+13% damage as Water damage | Water Resistance: +9% | Movement: +0.75 |
 Large Masterwork Rune |
Medium Masterwork Rune |
Medium Masterwork Rune |
Pixie Dust |
+13% damage as Physical damage | Maximum Physical Armour: +17% | Maximum Magic Armour: +17% |
 Large Rock Rune |
Medium Rock Rune |
Medium Rock Rune |
Pixie Dust |
+13% damage as Earth damage | Earth Resistance: +9% | Maximum Vitality: +84 |
 Large Thunder Rune |
Medium Thunder Rune |
Medium Thunder Rune |
Pixie Dust |
+13% damage as Air damage | Air Resistance: +9% | Dodging: +5% |
 Large Venom Rune |
Medium Venom Rune |
Medium Venom Rune |
Pixie Dust |
+13% damage as Poison damage | Poison Resistance: +9% | Accuracy: +12% |
| - | - | - | - | - | - | - |
 Giant Flame Rune |
Large Flame Rune |
Large Flame Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Fire damage | Fire Resistance: +11% | Critical Chance: +6% |
 Giant Frost Rune |
Large Frost Rune |
Large Frost Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Water damage | Water Resistance: +11% | Movement: +1 |
 Giant Masterwork Rune |
Large Masterwork Rune |
Large Masterwork Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Physical damage | Maximum Physical Armour: +21% | Maximum Magic Armour: +21% |
 Giant Rock Rune |
Large Rock Rune |
Large Rock Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Earth damage | Earth Resistance: +11% | Maximum vitality: +111 |
 Giant Thunder Rune |
Large Thunder Rune |
Large Thunder Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Air damage | Air Resistance: +11% | Dodging: +6% |
 Giant Venom Rune |
Large Venom Rune |
Large Venom Rune |
Pouch Of Superior Pixie Dust |
+15% damage as Poison damage | Poison Resistance: +11% | Accuracy: +16% |
| - | - | - | - | - | - | - |
 Small Flame Rune Of Power |
Small Flame Rune |
 Rune Frame Of Power |
Intelligence: +1 +9% damage as Fire Damage |
Intelligence: +1 Fire Resistance: +5% |
Intelligence: +1 Critical Chance: +3% |
|
 Medium Flame Rune Of Power |
Medium Flame Rune |
Rune Frame Of Power |
Intelligence: +2 +11% damage as Fire Damage |
Intelligence: +2 Fire Resistance: +7% |
Intelligence: +2 Critical Chance: +4% |
|
 Large Flame Rune Of Power |
Large Flame Rune |
Rune Frame Of Power |
Intelligence: +2 +13% damage as Fire Damage |
Intelligence: +2 Fire Resistance: +9% |
Intelligence: +2 Critical Chance: +5% |
|
 Giant Flame Rune of Power |
Giant Flame Rune |
Rune Frame Of Power |
ใ | Intelligence: +3 +15% damage as Fire Damage |
Intelligence: +3 Fire Resistance: +11% |
Intelligence: +3 Critical Chance: +6% |
| - | - | - | - | - | - | - |
 Small Frost Rune Of Power |
Small Frost Rune |
Rune Frame Of Power |
Intelligence: +1 +9% damage as Water damage |
Intelligence: +1 Water Resistance: +5% |
Intelligence: +1 |
|
 Medium Frost Rune Of Power |
Medium Frost Rune |
Rune Frame Of Power |
Intelligence: +2 +11% damage as Water damage |
Intelligence: +2 Water Resistance: +7% |
Intelligence: +2 Movement: +0.5 |
|
 Large Frost Rune Of Power |
Large Frost Rune |
Rune Frame Of Power |
Intelligence: +2 +13% damage as Water damage |
Intelligence: +2 Water Resistance: +9% |
Intelligence: +2 Movement: +0.75 |
|
 Giant Frost Rune of Power |
Giant Frost Rune |
Rune Frame of Power |
ใ | Intelligence: +3 +15% damage as Water damage |
Intelligence: +3 Water Resistance: +11% |
Intelligence: +3 Movement: +1 |
| - | - | - | - | - | - | - |
 Small Thunder Rune Of Power |
|
Rune Frame Of Power |
Finesse: +1 +9% damage as Air damage |
Finesse: +1 Air Resistance: +5% |
Finesse: +1 Dodging: +3% |
|
 Medium Thunder Rune Of Power |
|
Rune Frame Of Power |
Finesse: +2 +11% damage as Air damage |
Finesse: +2 Air Resistance: +7% |
Finesse: +2 Dodging: +4% |
|
 Large Thunder Rune Of Power |
|
Rune Frame Of Power |
Finesse: +2 +13% damage as Air damage |
Finesse: +2 Air Resistance: +9% |
Finesse: +2 Dodging: +5% |
|
 Giant Thunder Rune of Power |
Giant Thunder Rune |
Rune Frame of Power |
ใ | Finesse: +3 +15% damage as Air damage |
Finesse: +3 Air Resistance: +11% |
Finesse: +3 Dodging: +6% |
| - | - | - | - | - | - | - |
 Small Rock Rune Of Power |
|
Rune Frame Of Power |
Strength: +1 11% damage as Earth damage |
Strength: +1 Earth Resistance: +5% |
Strength: +1 Maximum vitality: +11 |
|
 Medium Rock Rune Of Power |
Medium Rock Rune |
Rune Frame Of Power |
Strength: +2 11% damage as Earth damage |
Strength: +2 Earth Resistance: +7% |
Strength: +2 Maximum vitality: +28 |
|
 Large Rock Rune Of Power |
Large Rock Rune |
Rune Frame Of Power |
Strength: +2 13% damage as Earth damage |
Strength: +2 Earth Resistance: +9% |
Strength: +2 Maximum vitality: +84 |
|
 Giant Rock Rune of Power |
Giant Rock Rune |
Rune Frame of Power |
ใ | Strength: +3 15% damage as Earth damage |
Strength: +3 Earth Resistance: +11% |
Strength: +3 Maximum vitality: +111 |
| - | - | - | - | - | - | - |
 Small Venom Rune Of Power |
Small Venom Rune |
Rune Frame Of Power |
Finesse: +1 +9% damage as Poison damage |
Finesse: +1 Poison Resistance: +5% |
Finesse: +1 Accuracy: +5% |
|
 Medium Venom Rune Of Power |
Medium Venom Rune |
Rune Frame Of Power |
Finesse: +2 +11% damage as Poison damage |
Finesse: +2 Poison Resistance: +7% |
Finesse: +2 Accuracy: +8% |
|
 Large Venom Rune Of Power |
Large Venom Rune |
Rune Frame Of Power |
Finesse: +2 +13% damage as Poison damage |
Finesse: +2 Poison Resistance: +9% |
Finesse: +2 Accuracy: +8% |
|
 Giant Venom Rune of Power |
Giant Venom Rune |
Rune Frame of Power |
ใ | Finesse: +3 +15% damage as Poison damage |
Finesse: +3 Poison Resistance: +11% |
Finesse: +3 Accuracy: +15% |
| - | - | - | - | - | - | - |
 Small Masterwork Rune of Power |
Small Masterwork Rune |
Rune Frame of Power |
ใ | Strength: +1 +9% damage as Physical damage |
Strength: +1 Maximum Physical Armour: +9% |
Strength: +1 Maximum Magic Armour: +9% |
 Medium Masterwork Rune of Power |
Medium Masterwork Rune |
Rune Frame of Power |
ใ | Strength: +2 +11% damage as Physical damage |
Strength: +2 Maximum Physical Armour: +13% |
Strength: +2 Maximum Magic Armour: +13% |
 Large Masterwork Rune of Power |
Large Masterwork Rune |
Rune Frame of Power |
ใ | Strength: +2 +13% damage as Physical damage |
Strength: +2 Maximum Physical Armour: +17% |
Strength: +2 Maximum Magic Armour: +17% |
 Giant Masterwork Rune of Power |
Giant Masterwork Rune |
Rune Frame of Power |
ใ | Strength: +3 +15% damage as Physical damage |
Strength: +3 Maximum Physical Armour: +21% |
Strength: +3 Maximum Magic Armour: +21% |
| - | - | - | - | - | - | - |
| Mystical Giant Flame Rune | Giant Flame Rune |
 Mystical Rune Frame |
ใ | Ranged: +1 +15% damage as Fire damage |
Huntsman: +1 Fire Resistance +11% |
Pyrokinetic: +1 Critical Chance: +6% |
| Mystical Giant Thunder Rune | Giant Thunder Rune |
Mystical Rune Frame |
ใ | Dual Wielding: +1 +15% damage as Air damage |
Scoundrel: +1 Air Resistance: +11% |
Aerothurge: +1 Dodging: +6% |
| Mystical Giant Venom Rune | Giant Venom Rune |
Mystical Rune Frame |
ใ | Perserverance: +1 +15% damage as Poison damage |
Summoning: +1 Poison Resistance: +11% |
Necromancer: +1 Accuracy: +16% |
| Mystical Giant Frost Rune | Giant Frost Rune |
Mystical Rune Frame |
ใ | Single-Handed: +1 +15% damage as Water damage |
Leadership: +1 Water Resistance: +11% |
Hydrosophist: +1 Movement: +1 |
| Mystical Giant Masterwork Rune | Giant Masterwork Rune |
Mystical Rune Frame |
ใ | Wits: +3 +15% damage as Physical damage |
Constitution: +3 Maximum Physical Armour +21% |
Memory: +3 Maximum Magic Armour: +21% |
| Mystical Giant Rock Rune | Giant Rock Rune |
Mystical Rune Frame |
ใ | Two-Handed: +1 +15% damage as Earth damage |
Warfare: +1 Earth Resistance: +11% |
Geomancer: +1 Maximum Vitality: +111 |
Version History:
v3.0.XXX.XXX:
- Corrected masterwork runes armor and amulet slot effects
v3.0.158.595:
- Fixed Rune screen not updating correctly when switching characters in controller mode
v3.0.150.188:
- Framed Frost runes and Framed Thunder runes now have the correct bonuses
- Improved tooltips for runes
v3.0.146.559:
- In the rune screen, you can now see all runes in all your party membersโ inventories
v3.0.143.324:
- Reverted a runeslot change that was released too soon. [Undo 3.0.143.148]
v3.0.143.148:
- Rune slots are now limited to one slot per item
AnonymousWondered if anyone tried, for making air runes does a gold coin count as a gold item?
- Anonymous
have some issues, i have read some issues added runes to empty slots, i made sure the item and rune is on the persons bag and the person was highlighted but i still can't add the rune to the item (weapon or amulet) i have 5 runes and tryed each one on each of the items but nothing happens. what am i doing wrong?
- Anonymous
The resistances for runes in armor are wrong. It's listed with 6/9/12/15, but it got reduced (?) to 5/7/9/11.
- Anonymous
Mystical Giant Masterwork Rune adds +3 Strength on an armor-slot instead of +3 Constitution
- Anonymous
"any wood" is wrong, so very wrong. i can't find wood ANYWHERE
- Anonymous
Incorrect Giant Rock Rune value for vitality. My game says +111 vitality instead of +203. Did the value get changed?
- Anonymous
Runes with +x% maximum armor increase whole armor or just Item they were put intro?
- Anonymous
Why do the giant mystical masterwork runes give a bonus +3 when all others just give +1? As of now, there is absolutely no reason a 2h melee fighter would use a giant mystical rock rune (+1 2h, +15% earth dmg) over a giant masterwork rune of power (+3 str, +15% physical dmg), right? The +3 strength will boost your dmg way more than the +1 2h I would think, plus the other added damage stacks onto the physical dmg the sword is already dealing, instead of spreading it out over the 2 armor types.
- Anonymous
The listed resistance values for all the runes seem high (playing definitive edition). Giant runes give +11% resistance (on armor).
- Anonymous
Mystical Giant Masterwork Rune gives Constitution: +1 and maximum Physical Armour: +21%, not +40%.
- Anonymous
Were the medium runes split so your slots in the c4afting table were 1 med, 1 med and 1 pixie dust? Also were can the list of what item types can have a rune slot, I have been looking everywhere and all that comes up is the old 3 runes to 1 forumns.
- Anonymous
Does one need to find the book for crafting a specific (size) rune or can one 'learn' the recipe by trying different combinations of items and discovering it? I'm asking because, e.g. I don't have the recipe for large flame rune among the recipes learned, so I looked it up in the table here and then tried to combine 2 medium flame runes + pixie dust and it didn't work (invalid combination).
The Mystical Giant Venom Rune gives me +11% poison resistance, instead of +15% as written above, in addition to the +1 summoning.
- Anonymous
FIrst frame can be found in a basement in Driftwood, where there's a lmprisioned lich (can't recall its name). From then on, just check vendors.
- Anonymous
Obviously something does not work in your gameplay, at level 16 I have my 4 pg party full rune/mystic/power (16 runes in total). I confirm the nerf to the crit% of the flame runes.
- Anonymous
In the definitive edition the flame runes have been nerfed greatly, they only give 3/4/5/6% crit chance now
- Anonymous
- Anonymous
- Anonymous
hi I think I found a couple mistakes, I just crafted those runes and below are only the differences from the above:
- "Mystical Giant Flame Rune" => (W) 9% as fire dmg
- "Mystical Giant Thunder Rune" => (Ar) 15% Air res(Am) 6% Dodge
- "Mystical Giant Frost Rune" => (W) 11% as water dmg (Ar) 15% Water res (Am) 1 mov
- "Mystical Giant Rock Rune" => (W) 13% as Earth dmg
- "Giant Flame Rune of Power" => (W) 9% as Fire dmg
- "Giant Thunder Rune of Power" => (Ar) 15% Air res
- "Giant Frost Rune of Power" => (Ar) 15% Water res (Am) 1 mov
- "Giant Master Rune of Power" => (W) 2 str (Ar) 2 str and 30% phys armour (Am) 2 str and 30% mag armour
- "Giant Rock Rune of Power" => (W) 13% as Earth dmg
I am not sure if the reduction in some of the effects is intentional as a balance for the added attribute by the mystical/power runes or not but I hope that if some of these were nor intended someone notice this. Thanks
- Anonymous
hi I think I found a mistake, I just crafted the "Mystical Giant Flame Rune" and the description says it adds Ranger 1 and 9% as fire damage not 15%.
- Anonymous
Giant Thunder Rune of Power, when inserted into a necklace gives Finesse: +3 and Movement: +1.
- Anonymous
- Anonymous
Does the +crit from Flame Runes give spells the ability to crit, or does one still need to pick up the talent?
Wits potion does not stack
3
+10
-1